Efficacy and safety of 6% hydroxyethyl starches 130/0.4 (Voluven®) for perioperative volume replacement in children undergoing cardiac surgery: a propensity-matched analysis
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چکیده
Efficacy and safety of 6% hydroxyethyl starches 130/0.4 (Voluven®) for perioperative volume replacement in children undergoing cardiac surgery: a propensity-matched analysis Critical Care Sample doi:10.1186/s13054-015-0830-z Philippe Van der Linden ([email protected]) Melanie Dumoulin ([email protected]) Celine Van Lerberghe ([email protected]) Cristel Sanchez Torres ([email protected]) Ariane Willems ([email protected]) David Faraoni ([email protected]) Sample
منابع مشابه
Efficacy and safety of 6% hydroxyethyl starch 130/0.4 (Voluven) for perioperative volume replacement in children undergoing cardiac surgery: a propensity-matched analysis
INTRODUCTION Six percent hydroxyethyl starch (HES) 130/0.4 is considered an alternative to human albumin (HA) and crystalloids for volume replacement in children undergoing cardiac surgery. In this large propensity-matched analysis, we aimed to assess the efficacy and safety of replacing HA with HES for intraoperative volume therapy in children undergoing cardiac surgery with cardiopulmonary by...
متن کاملThe dose of hydroxyethyl starch 6% 130/0.4 for fluid therapy and the incidence of acute kidney injury after cardiac surgery: A retrospective matched study
The safety of hydroxyethyl starches (HES) is still under debate. No studies have compared different dosing regimens of HES in cardiac surgery. We analyzed whether the incidence of Acute Kidney Injury (AKI) differed taking into account a weight-adjusted cumulative dose of HES 6% 130/0.4 for perioperative fluid therapy. This retrospective cohort study included all adult patients undergoing electi...
متن کاملSix percent hydroxyethyl starch 130/0.4 (Voluven®) versus 5% human serum albumin for volume replacement therapy during elective open-heart surgery in pediatric patients.
BACKGROUND Although 5% albumin (human serum albumin [HSA]) is widely used in cardiac surgery children, synthetic colloids may provide a valuable alternative. This study compared 6% hydroxyethyl starch (HES) 130/0.4 with HSA for volume replacement in this population. METHODS The study was a two-center, randomized, controlled, parallel-group, double-blind trial performed in children aged 2-12 y...
متن کاملPerioperative clinical and economic outcomes associated with replacing first-generation high molecular weight hydroxyethyl starch (Hextend®) with low molecular weight hydroxyethyl starch (Voluven®) at a large medical center
BACKGROUND Several plasma volume expander alternatives exist to enhance intravascular volume status in patients undergoing surgery. The optimal intravascular volume expander in the perioperative setting is currently unknown. Low molecular weight hetastarch, Voluven® (130/0.4), may have a better safety profile than high molecular weight hetastarch, Hextend® (450/0.7). We examined the clinical an...
متن کاملVoluven, a new colloid solution.
Hydroxyethyl starch (HES) 130/0.4 (Voluven, Fresenius/Hospira, Germany) is indicated for the treatment and prophylaxis of hypovolemia. As the Voluven molecule is smaller than those of other available hydroxyethyl starch products, it is associated with less plasma accumulation and can be safely used in patients with renal impairment. Previous studies have demonstrated that Voluven has comparable...
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